ConclusionsĪll planktonic cells of the different Candida species tested are susceptible to <1 mg/ml A. sativum oil, and 91.7% were resistant to fluconazole. Regarding susceptibilities in biofilms, 43.8% of biofilms were resistant to A.
sativum, whereas 4.2% were resistant to fluconazole. ResultsĪll planktonic Candida isolates were susceptible to the essential oil of A. The isolates were also evaluated by semiquantitative XTT reduction. sativum and fluconazole against both biofilm and planktonic cells were evaluated using the Clinical & Laboratory Standards Institute (CLSI) M27-A3 method. For each isolate, the antifungal activities of the essential oil of A. albicans, Candida glabrata, Candida tropicalis, and Candida krusei. MethodsĪ total of 48 clinical isolates obtained from the acrylic surface of partial or complete dentures were examined, and the following species were identified: C. sativum and fluconazole against clinical isolates of Candida species obtained from rigid, acrylic-based partial or total dentures and to compare these agents’ effects on both biofilm and planktonic cells. The objective of this study was to determine the antifungal activities of the essential oil of A. Meanwhile, the oil of Allium sativum has shown an effect in controlling biofilm formation by C. In this context, the use of fluconazole has been proposed, but its disadvantage is microbial resistance. The colonization of the surfaces of dental prostheses by Candida albicans is associated with the development of denture stomatitis.
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